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High-Purity Aniline Derivative for Agrochemical & API Synthesis
|
Parameter
|
Specification
|
|---|---|
|
Chemical Name |
2-Methyl-3-(trifluoromethyl)aniline |
|
CAS Number |
54396-44-0 |
|
Molecular Formula |
C₈H₈F₃N |
|
Molecular Weight |
175.15 g/mol |
|
Purity |
≥99.0% (GC) |
|
Appearance |
Colorless to pale yellow liquid |
PRECISE ALKYLATION AGENT
RELIABLE SUPPLY CHAIN
TAILORED PACKING SOLUTIONS
TUODA’s 2-Methyl-3-(trifluoromethyl)aniline is a high-purity aromatic amine used in the synthesis of active pharmaceutical ingredients, agrochemical actives, and electronic chemicals. With ≥99.0% purity and tight moisture control, it ensures clean downstream reactions, reproducible process performance, and excellent selectivity for halogenated intermediates.
2-Methyl-3-(trifluoromethyl)aniline (CAS 54396-44-0) is a halogenated aniline derivative widely utilized in regulated synthetic routes that demand precise electron-withdrawing effects. Its unique CF₃ substituent and ortho-methyl configuration make it ideal for building sterically and electronically optimized intermediates. TUODA guarantees low residual solvents and consistent batch performance, meeting the stringent quality standards of global chemical manufacturers.
Manufactured in GMP-compliant facilities, TUODA ensures strict batch consistency, controlled distillation, and safe, inert-gas packaging for global industrial applications.
Industry-Leading Quality Parameters for Triethylaluminu
All data verified by TUODA’s ISO 9001-certified lab. Full COA, MSDS, GC/NMR data available upon request.
Why TUODA’s 2-Methyl-3-(trifluoromethyl)aniline Sets the Industry Standard
Pharmaceutical-grade purity ≥99.0%, minimizing side reactions and ensuring high reactivity in complex synthesis.
Stabilized for storage and transport, ensuring purity and performance throughout demanding conditions.
Enables high-yield, selective transformations in regulated, fluorine-sensitive chemical systems.
Backed by over 10 years of fluorine compound expertise, TUODA offers full-cycle support for 2-Methyl-3-(trifluoromethyl)aniline applications.
Experience the confidence of working with TUODA’s high-purity 2-Methyl-3-(trifluoromethyl)aniline in your advanced synthesis projects.
2-Methyl-3-(trifluoromethyl)aniline's Versatile Role in Modern Industrial Processes
Critical building block for targeted therapeutics, leveraging its unique trifluoromethyl substitution pattern to enhance metabolic stability and binding affinity in kinase inhibitors and CNS-active compounds.
Essential precursor in developing next-generation fungicides and insecticides with enhanced target specificity, environmental persistence control, and reduced application rates through strategic fluorine incorporation.
Key intermediate for synthesizing high-performance polymers, liquid crystals, and specialty materials where the trifluoromethyl group imparts unique thermal stability, chemical resistance, and optical properties.
Valuable precursor for high-performance colorants with enhanced lightfastness, chemical stability, and color intensity, particularly in industrial applications requiring resistance to harsh conditions.
Strategic component in the synthesis of organic semiconductors, photoresist materials, and electronic chemical formulations where the trifluoromethyl group enhances electron-transport properties and processing characteristics.
Indispensable building block for medicinal chemistry exploration, fluorine-based methodology development, and structure-activity relationship studies across pharmaceutical and agrochemical research programs.
2-Methyl-3-(trifluoromethyl)aniline represents a high-value building block in modern pharmaceutical synthesis, offering a unique substitution pattern that combines the steric influence of the methyl group with the electronic properties of the trifluoromethyl functionality to optimize drug candidate profiles.
Our pharmaceutical-grade 2-methyl-3-(trifluoromethyl)aniline is manufactured under stringent quality control protocols, ensuring exceptional purity (≥99.5%) and batch-to-batch consistency required for regulated pharmaceutical manufacturing processes.
A leading pharmaceutical company utilized TUODA's 2-methyl-3-(trifluoromethyl)aniline as a key building block in their development of a novel JAK inhibitor, where the strategic positioning of the trifluoromethyl group improved target selectivity 8-fold over previous candidates while extending the metabolic half-life by 4.2 hours, significantly enhancing the compound's therapeutic window.
2-Methyl-3-(trifluoromethyl)aniline serves as an essential precursor in modern agrochemical development, where the strategic incorporation of fluorine dramatically enhances biological activity, environmental persistence control, and overall efficacy profiles of crop protection agents.
Our technical-grade 2-methyl-3-(trifluoromethyl)aniline meets the demanding requirements of agrochemical synthesis, providing the high purity and consistent quality essential for developing effective and environmentally responsible crop protection solutions.
A major agrochemical developer incorporated our 2-methyl-3-(trifluoromethyl)aniline in their synthesis of a novel strobilurin-class fungicide, achieving exceptional control of resistant pathogen strains at application rates 35% lower than conventional products, while demonstrating improved photostability that extended effective field protection by 12-14 days.
2-Methyl-3-(trifluoromethyl)aniline functions as a key intermediate in the synthesis of high-performance fluorinated materials, where the trifluoromethyl group imparts exceptional thermal stability, chemical resistance, and unique surface properties to the resulting polymers and specialty materials.
Our high-purity 2-methyl-3-(trifluoromethyl)aniline enables the consistent production of advanced fluorinated materials with the precise specifications required for demanding industrial applications across multiple sectors.
A specialty materials manufacturer utilized our 2-methyl-3-(trifluoromethyl)aniline to develop a novel fluorinated polyamide for semiconductor processing equipment components, achieving exceptional plasma resistance with a 300% improvement in service lifetime, while maintaining dimensional stability at operating temperatures up to 280°C.
2-Methyl-3-(trifluoromethyl)aniline serves as a valuable precursor in the synthesis of high-performance colorants where the trifluoromethyl group enhances lightfastness, chemical stability, and color intensity through its unique electronic effects on chromophore systems.
Our ultra-pure 2-methyl-3-(trifluoromethyl)aniline provides the consistent quality required for colorant manufacturing, ensuring reproducible shade development and performance characteristics across production batches.
A leading industrial colorant producer incorporated our 2-methyl-3-(trifluoromethyl)aniline in their development of a new series of high-performance pigments for automotive coatings, achieving exceptional weather resistance with less than 5% color shift after 4,000 hours of accelerated weathering testing, while maintaining excellent chemical resistance against automotive fluids and cleaning agents.
2-Methyl-3-(trifluoromethyl)aniline plays a strategic role in the development of advanced electronic materials, where the electron-withdrawing trifluoromethyl group modifies electronic properties while the methyl substituent influences molecular packing and processing characteristics.
Our electronic-grade 2-methyl-3-(trifluoromethyl)aniline is manufactured with exceptionally low metal content (<5 ppb) and stringent purity specifications to meet the demanding requirements of electronic materials production.
A specialty electronic materials company utilized our high-purity 2-methyl-3-(trifluoromethyl)aniline to develop a novel n-type organic semiconductor material, achieving electron mobility values of 3.2 cm²/Vs with excellent air stability, enabling the fabrication of flexible electronic devices with significantly improved performance and reliability under ambient conditions.
2-Methyl-3-(trifluoromethyl)aniline serves as an indispensable building block in cutting-edge research across pharmaceutical, agrochemical, and materials science domains, enabling scientists to explore the unique properties conferred by strategic fluorine incorporation.
We offer research-grade 2-methyl-3-(trifluoromethyl)aniline in various package sizes suitable for laboratory use, with comprehensive analytical documentation and technical support for research scientists.
A university medicinal chemistry laboratory utilized our high-purity 2-methyl-3-(trifluoromethyl)aniline in their investigation of novel fluorinated scaffolds for neurological targets, identifying a promising lead compound with exceptional blood-brain barrier penetration and nanomolar potency against a previously undruggable protein-protein interaction implicated in neurodegenerative disorders.
Discover how our high-purity 2-Methyl-3-(trifluoromethyl)aniline can enhance your specific application
Industry-Leading 2-Methyl-3-(trifluoromethyl)aniline with Exceptional Purity and Stabilit
| Chemical Formula: | C₈H₈F₃N |
| Molecular Weight: | 175.15 g/mol |
| CAS Number: | 54396-44-0 |
|
Parameter
|
Standard Grade
|
High-Purity Grade
|
Ultra-Pure Grade
|
|---|---|---|---|
|
Purity (GC) |
≥98.0% |
≥ 99.0% |
≥ 99.5% |
|
Moisture (KF) |
≤ 0.5% |
≤ 0.2% |
≤ 0.1% |
|
Residue on Ignition |
≤ 0.1% |
≤ 0.05% |
≤ 0.02% |
|
Chloride (Cl⁻) |
≤ 100 ppm |
≤ 50 ppm |
≤ 10 ppm |
|
Heavy Metals (Pb) |
≤ 20 ppm |
≤ 10 ppm |
≤ 5 ppm |
|
Property
|
Value
|
|---|---|
|
Appearance |
Transparent to slightly yellow liquid |
|
Density |
1.238 g/cm³ at 25°C |
|
Melting Point |
14–18°C |
|
Boiling Point |
188–192°C at 760 mmHg |
|
Flash Point |
79°C (closed cup) |
|
Solubility |
Insoluble in water, soluble in organic solvents (e.g., methanol, ether, DCM) |
While relatively stable under ambient conditions, the compound should be kept away from strong oxidizers and heat sources.
Although not highly hygroscopic, 2-Methyl-3-(trifluoromethyl)aniline should be stored in tightly sealed containers to prevent trace moisture interference during synthesis.
Compatible with most fluorinated solvent systems, glass, and stainless steel. Avoid prolonged exposure to reactive acids or alkalis.
Stable under 0–30°C storage. Prolonged exposure above 50°C may reduce purity. Store in cool, dry, and ventilated areas.
Our technical team is available to provide detailed specifications, safety information, and handling guidelines for our 2-Methyl-3-(trifluoromethyl)aniline products.
Rigorous Testing and Strict Quality Management for Consistent Excellence
Each batch of incoming raw materials undergoes rigorous testing to verify purity and compliance with specifications before entering production.
Continuous monitoring throughout the production process with real-time analytics to ensure consistency and detect any deviations immediately.
Comprehensive analysis of each production batch against all specified parameters using advanced analytical techniques.
Application-specific testing to verify product performance in simulated customer processes, ensuring it meets real-world requirements.
Comprehensive documentation package including Certificate of Analysis, traceability records, and quality assurance documentation.
Our quality management system is certified to ISO 9001:2015, ensuring consistent processes and continuous improvement.
Environmental management certification demonstrating our commitment to sustainable manufacturing practices.
Occupational Health and Safety Management System certification for safe handling of hazardous materials.
Compliant with European Union's Registration, Evaluation, Authorization and Restriction of Chemicals regulation.
Our state-of-the-art QC laboratory is equipped with advanced analytical instrumentation to ensure batch-to-batch consistency, exceptional purity, and compliance with regulatory requirements for 2-Methyl-3-(trifluoromethyl)aniline in high-value applications.
For quantitative determination of assay (purity ≥99.0%) and identification of trace aromatic impurities.
To monitor and limit heavy metals (Pb, Fe, Cu, etc.) to below regulatory thresholds.
For precise measurement of residual moisture (<0.2%) ensuring product stability and performance.
For functional group confirmation and verification of fluorinated aniline structure.
We partner with our customers to ensure our products meet their specific quality requirements through our comprehensive quality assurance program:
We develop custom specifications to match your unique process requirements.
Tailored quality standards are provided based on your end-use application.
We offer formulation flexibility to meet specialized technical demands.
Each product is adjusted to ensure compatibility with your production line.
Regulatory and safety parameters are aligned with your regional compliance.
Regulatory and safety parameters are aligned with your regional compliance.
Still have questions? Here are answers to the most common queries buyers ask when sourcing high-purity 2-Methyl-3-(trifluoromethyl)aniline.
Our MOQ starts at 100g for lab use and 1kg for commercial evaluation. We support flexible order sizes to meet both R&D and scale-up needs.
Yes. Samples (10–50g) are available upon request for quality evaluation. COA and SDS will be provided with each sample.
Absolutely. We offer custom purity levels (up to 99.5%), inhibitor-free options, and packaging in sealed glass bottles, HDPE drums, or fluorinated containers depending on your regulatory and process needs.
This product is not classified as a UN hazardous material, but may require controlled temperature or ventilation labeling depending on local transport rules. Our logistics team ensures full compliance.
We can provide the following documentation upon request:
COA
SDS (GHS-compliant)
Third-party lab testing
TDS and reach registration support (if required)
Store in a cool, dry, and ventilated area, away from direct light, ignition sources, or acids. Recommended storage temperature: ≤25°C, sealed tightly to prevent hydrolysis or degradation.
Standard stock ships within 3–5 business days. For made-to-order high-purity or custom grades, lead time is usually 7–14 days depending on production slot and packaging.
Yes. Our team supports:
Global regulatory documentation (REACH/TSCA/etc.)
Impurity profiling
Custom formulation compatibility checks
Analytical method transfer upon NDA
TUODA combines ISO-certified quality systems, GMP-aligned production, custom synthesis flexibility, and over 10 years of export experience. We offer consistent purity, traceable documentation, and responsive service for demanding pharma and fine chemical customers.
Can’t find your question here? Our team is ready to assist you 1-on-1.
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Contact us today to receive a free quote and expert consultation on chemical intermediates and petrochemical solutions. Tuoda is ready to provide the perfect solution for your project.
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