High-Purity 3,5-Dimethylpiperidine for Pharmaceutical & Fine Chemical Synthesis

Exceptional Quality, Consistent Reactivity, and Global Supply Assurance for Advanced Organic Applications

Ultra-High Purity Grade

3,5-Dimethylpiperidine

High-Purity Aliphatic Amine for API Synthesis & Specialty Chemical Applications

Parameter
Specification

Chemical Name

3,5-Dimethylpiperidine

CAS Number

35794-11-7

Molecular Formula

C7H15N

Molecular Weight

115.22 g/mol

Purity

≥99.0% (GC)

Appearance

Clear to pale yellow transparent liquid

PRECISE ALKYLATION AGENT
RELIABLE SUPPLY CHAIN
TAILORED PACKING SOLUTIONS

High-Purity 3,5-Dimethylpiperidine

The Ideal Intermediate for Agrochemical & Pharmaceutical Synthesis

TUODA’s 3,5-Dimethylpiperidine is a premium-grade alicyclic amine valued for its purity, reactivity, and compatibility with sensitive organic reactions. With ≥99.0% purity and controlled moisture, it enables efficient synthesis of APIs, agro-intermediates, and performance materials—especially in reductive amination, alkylation, and heterocycle formation.

3,5-Dimethylpiperidine (CAS 35794-11-7) is a structurally defined nitrogen heterocycle offering exceptional steric control and reactivity in complex chemical transformations. TUODA ensures low residual solvents and high batch consistency, supporting high-throughput pharmaceutical R&D and industrial-scale synthesis.

Produced in GMP-compliant facilities, our 3,5-DMP is refined through multi-step distillation and rigorous QC, delivering reliable performance across regulated environments and demanding process requirements.

Product Specifications

Industry-Leading Purity & Stability for High-Performance Chemical Synthesis

Chemical Properties

Chemical Formula: C7H15N
Molecular Weight: 115.22 g/mol
Purity: ≥99.0% (GC)
Appearance: Colorless to light yellow transparent liquid
Density: 0.813 g/cm³ @ 25°C

Physical Properties

Boiling Point: 137–139°C
Melting Point: −50°C (approx.)
Flash Point: 29°C (closed cup)
Viscosity: Low viscosity
Solubility: Soluble in most organic solvents such as ether, methanol, and toluene

Packaging & Storage

Available Sizes: 100g, 500g, 1kg, 5L
Container Type: Sealed amber bottles or stainless steel drums
Storage Temp: 0°C to +30°C (keep sealed and away from moisture and light)
Shelf Life: 12 months under recommended storage
Handling: Store under inert gas (argon or nitrogen); avoid air/moisture contact

All specifications are validated under strict QA protocols. Customized COA, SDS, and analytical reports are available upon request.

Core Advantages

Why TUODA’s 3,5-Dimethylpiperidine (3,5-Dimethylpiperidine) Is the Preferred Choice for Agrochemical & Pharmaceutical Synthesis

Ultra-High Purity

Industry-grade 3,5-Dimethylpiperidine with ≥99.0% GC purity minimizes undesired by-products and enhances reproducibility in fine chemical and pharmaceutical applications.

Enhanced Stability

TUODA’s 3,5-Dimethylpiperidine is stabilized through inert-gas blanketing and moisture-tight packaging, ensuring long-term integrity and performance.

Superior Performance

3,5-Dimethylpiperidine is a sterically hindered secondary amine, ideal for key steps in building piperidine scaffolds and nitrogen-containing heterocycles.

Expert Technical Support

TUODA provides comprehensive support to help you streamline development and scale-up with 3,5-Dimethylpiperidine.

Experience the reliability and performance TUODA’s 3,5-Dimethylpiperidine brings to your synthesis workflow.

Application Areas

3,5-Dimethylpiperidine's Versatile Role in Modern Industrial Processes

Pharmaceutical Intermediates

Primary application as a key building block for pharmaceutical compounds, providing unique structural features for drug candidates targeting neurological and cardiovascular disorders.

Agrochemical Synthesis

Used as a versatile intermediate in the production of modern crop protection agents, contributing to enhanced efficacy and environmental profiles of next-generation pesticides.

Catalyst Development

Serves as a structural component in novel organocatalysts and ligand systems for asymmetric synthesis, enabling highly selective transformations in complex molecule synthesis.

Specialty Chemical Production

Functions as a reactive intermediate in the synthesis of specialty additives for polymers, lubricants, and surface treatment agents requiring sterically defined amine components.

Material Science Applications

Utilized in the development of advanced materials including corrosion inhibitors, epoxy curing agents, and components for specialized coatings with enhanced performance properties.

Research & Development

Essential building block in academic and industrial research for developing novel heterocyclic compounds and exploring structure-activity relationships in medicinal chemistry.

Pharmaceutical Intermediates

3,5-Dimethylpiperidine in Pharmaceutical Intermediates

3,5-Dimethylpiperidine serves as a crucial building block in pharmaceutical synthesis, offering unique structural features that contribute to improved pharmacokinetic profiles and target selectivity in drug candidates.

Key Benefits in Pharmaceutical Applications:

  • Provides conformationally restricted piperidine scaffold for enhanced receptor binding
  • Contributes to improved metabolic stability of drug candidates
  • Enables fine-tuning of lipophilicity and membrane permeability
  • Serves as a versatile intermediate for diverse heterocyclic compounds

Our high-purity 3,5-dimethylpiperidine ensures consistent performance in pharmaceutical synthesis, resulting in reliable yields and purity profiles essential for regulated pharmaceutical manufacturing.

Case Study: CNS Drug Development

A leading pharmaceutical company incorporated TUODA's 3,5-dimethylpiperidine in their synthesis of a novel CNS-active compound, achieving improved blood-brain barrier penetration and 3.5x higher target selectivity compared to their previous lead compound, significantly advancing their clinical development timeline.

Agrochemical Synthesis

3,5-Dimethylpiperidine in Agrochemical Synthesis

3,5-Dimethylpiperidine plays an important role in modern agrochemical development, serving as a key structural component in next-generation crop protection agents with improved efficacy and environmental profiles.

Applications in Agrochemicals:

  • Structure modification of insecticides for enhanced target specificity
  • Development of herbicides with improved rain-fastness properties
  • Synthesis of fungicides with optimized systemic activity
  • Creation of plant growth regulators with controlled release characteristics

Our ultra-high purity 3,5-dimethylpiperidine delivers consistent performance in agrochemical synthesis, critical for developing products with precise biological activity and safety profiles.

Case Study: Advanced Fungicide Development

A major agrochemical producer utilized our 3,5-dimethylpiperidine in their development of a novel systemic fungicide, achieving 40% longer persistence in field conditions and significantly reduced application rates while maintaining efficacy, resulting in an improved environmental profile.

Catalyst Development

3,5-Dimethylpiperidine in Catalyst Development

3,5-Dimethylpiperidine serves as a valuable structural element in the development of novel catalytic systems, particularly in asymmetric synthesis where its defined stereochemical environment contributes to selective transformations.

Catalyst Applications:

  • Component in chiral organocatalysts for asymmetric transformations
  • Structure element in ligand systems for transition metal catalysis
  • Modifier for heterogeneous catalysts to enhance selectivity
  • Building block for phase-transfer catalysts with improved efficiency

Our pharmaceutical-grade 3,5-dimethylpiperidine is produced under strict quality control, ensuring the high purity essential for developing precisely defined catalytic systems.

Case Study: Asymmetric Hydrogenation Catalyst

A specialty catalyst manufacturer incorporated our 3,5-dimethylpiperidine into a novel ligand system for asymmetric hydrogenation, achieving 98.5% enantiomeric excess in challenging substrate classes where conventional catalysts typically delivered less than 85% ee.

Specialty Chemical Production

3,5-Dimethylpiperidine in Specialty Chemical Production

3,5-Dimethylpiperidine is extensively used in specialty chemical synthesis as a versatile intermediate for various additives and functional compounds requiring specific steric and electronic properties.

Applications in Specialty Chemicals:

  • Synthesis of polymer stabilizers with enhanced thermal resistance
  • Production of fuel and lubricant additives with improved performance
  • Preparation of specialty surfactants for demanding applications
  • Development of corrosion inhibitors with targeted metal affinity

Our 3,5-dimethylpiperidine provides consistent quality and reactivity, critical factors in the production of high-value specialty chemicals with precise specifications.

Case Study: Advanced Lubricant Additive

A leading lubricant additive manufacturer implemented our 3,5-dimethylpiperidine in their synthesis of a next-generation anti-wear agent, achieving 30% improved thermal stability and significantly enhanced metal surface interaction, resulting in superior performance in high-pressure applications.

Material Science Applications

3,5-Dimethylpiperidine in Material Science Applications

3,5-Dimethylpiperidine plays an important role in advanced materials development, particularly in specialized coatings, epoxy systems, and corrosion inhibition technologies requiring defined amine functionality.

Material Science Applications:

  • Component in high-performance epoxy curing agents
  • Precursor for corrosion inhibitors with enhanced metal adhesion
  • Building block for UV-stabilizers in specialty coatings
  • Intermediate for surface modifiers with controlled hydrophobicity

Our industrial-grade 3,5-dimethylpiperidine delivers reliable performance in materials applications, with the consistency required for reproducible product properties.

Case Study: Advanced Coating Development

A specialty coatings manufacturer utilized our 3,5-dimethylpiperidine in developing a new marine coating system, achieving 65% improved corrosion resistance in salt-spray testing and significantly enhanced adhesion to metal substrates under extreme conditions.

Research & Development

3,5-Dimethylpiperidine in Research and Development

3,5-Dimethylpiperidine is an essential building block in academic and industrial research, enabling the exploration of novel heterocyclic compounds and structure-activity relationships in medicinal chemistry and materials science.

R&D Applications:

  • Development of novel biologically active heterocycles
  • Investigation of structure-activity relationships in drug design
  • Exploration of new synthetic methodologies
  • Creation of molecular libraries for high-throughput screening

We offer research-grade 3,5-dimethylpiperidine in various package sizes suitable for laboratory use, with comprehensive analytical documentation and technical support.

Case Study: Novel Scaffold Development

A university medicinal chemistry group utilized our high-purity 3,5-dimethylpiperidine to develop a novel scaffold for kinase inhibitors, identifying a promising lead compound with nanomolar activity against a previously challenging oncology target, leading to a research collaboration with a major pharmaceutical company.

Discover how our high-purity 3,5-Dimethylpiperidine can enhance your specific application

Chemical Properties & Specifications

Industry-Leading 3,5-Dimethylpiperidine with Exceptional Purity and Performance

3,5-Dimethylpiperidine Molecular Structure

Chemical Formula:

C₇H₁₅N

Molecular Weight:113.20 g/mol
CAS Number:35794-11-7

Product Specifications

Parameter
Standard Grade
High-Purity Grade
Ultra-Pure Grade

Assay (GC)

≥ 97.0%

≥ 98.5%

≥ 99.0%

Moisture (Karl Fischer)

≤ 0.2%

≤ 0.1%

≤ 0.05%

Amines/Impurities

≤ 1.0%

≤ 0.5%

≤ 0.2%

Peroxides

ND

ND

ND

Color (APHA)

≤ 50

≤ 30

≤ 10

Physical Properties

Property
Value

Appearance

Colorless to pale yellow transparent liquid

Density

0.816 g/cm³ @ 25°C

Melting Point

–30°C

Boiling Point

154–156°C

Flash Point

35°C (closed cup)

Solubility

Soluble in ether, alcohol, chloroform, and most organic solvents

Reactivity & Handling

Volatility & Flammability

Highly flammable liquid. Avoid exposure to heat, sparks, or open flames. Store in a well-ventilated, flame-proof environment.

Air & Moisture Sensitivity

Sensitive to air and moisture; may form irritating vapors. Store under nitrogen or argon atmosphere in tightly sealed containers.

Chemical Compatibility

Compatible with most non-acidic organic solvents. Avoid contact with oxidizers or strong acids.

Thermal Stability

Stable under standard storage temperatures (0–30°C). Avoid extended heating above 100°C to prevent degradation.

Packaging & Storage Information

Standard Packaging

  • 400 kg stainless steel cylinders
  • 1,600 kg ISO containers
  • 20,000 kg tank trucks

Storage Requirements

  • Store in cool, dry area (-10°C to +30°C)
  • Keep away from heat, sparks, and direct sunlight
  • Maintain inert gas blanket (nitrogen)
  • Segregate from incompatible materials

Documentation

  • Certificate of Analysis (CoA)
  • Safety Data Sheet (SDS)
  • Technical Data Sheet (TDS)
  • Handling & Storage Guidelines

Need Technical Information?

Our technical team is available to provide detailed specifications, safety information, and handling guidelines for our 3,5-Dimethylpiperidine products.

Quality Control & Assurance

Rigorous Testing and Strict Quality Management for Consistent Excellence

Raw Material Inspection

Each batch of incoming raw materials undergoes rigorous testing to verify purity and compliance with specifications before entering production.

In-Process Monitoring

Continuous monitoring throughout the production process with real-time analytics to ensure consistency and detect any deviations immediately.

Final Product Testing

Comprehensive analysis of each production batch against all specified parameters using advanced analytical techniques.

Performance Validation

Application-specific testing to verify product performance in simulated customer processes, ensuring it meets real-world requirements.

Documentation & Certification

Comprehensive documentation package including Certificate of Analysis, traceability records, and quality assurance documentation.

Quality Standards & Certifications

ISO 9001:2015

Our quality management system is certified to ISO 9001:2015, ensuring consistent processes and continuous improvement.

ISO 14001:2015

Environmental management certification demonstrating our commitment to sustainable manufacturing practices.

OHSAS 18001

Occupational Health and Safety Management System certification for safe handling of hazardous materials.

REACH Registered

Compliant with European Union's Registration, Evaluation, Authorization and Restriction of Chemicals regulation.

Lab technician performing quality control test on chemical sample at TUODA factory laboratory

State-of-the-Art Quality Control Laboratory

Our state-of-the-art quality control lab is equipped with specialized instruments to ensure the precise evaluation of 3,5-Dimethylpiperidine (3,5-DMP) across multiple analytical dimensions, including purity, residual solvents, moisture, and trace impurities.

Gas Chromatography (GC)

For quantitative analysis of 3,5-DMP purity and profiling of organic volatile impurities (OVIs)

Inductively Coupled Plasma (ICP-MS)

To detect trace metal impurities down to ppb levels

Karl Fischer Titration

For precise determination of residual water content to ensure stability during storage and application

FTIR Spectroscopy

For functional group confirmation and fingerprint identification of 3,5-DMP

Our Quality Commitment

100% Batch Testing

Full Traceability

Detailed Documentation

Secure Chain of Custody

Customer Quality Assurance Program

We partner with our customers to ensure our products meet their specific quality requirements through our comprehensive quality assurance program:

We develop custom specifications to match your unique process requirements.

Tailored quality standards are provided based on your end-use application.

We offer formulation flexibility to meet specialized technical demands.

Each product is adjusted to ensure compatibility with your production line.

Regulatory and safety parameters are aligned with your regional compliance.

Regulatory and safety parameters are aligned with your regional compliance.

Technicians in cleanroom suits operating stainless steel reactor and control panel in pharmaceutical facility

Ready to experience our quality difference?

Frequently Asked Questions About 3,5-Dimethylpiperidine

Still unsure about sourcing or handling high-purity 3,5-Dimethylpiperidine? Here are answers to the most common questions we receive from global chemical and pharmaceutical buyers:

Still unsure about sourcing or handling high-purity 3,5-Dimethylpiperidine? Here are answers to the most common questions we receive from global chemical and pharmaceutical buyers:

Yes, samples of ≥99.0% pure 3,5-Dimethylpiperidine are available for qualified clients. Standard sample size is 100g in sealed glass bottles with COA and MSDS provided.

 

Absolutely. We offer:

  • Customized packaging: glass bottles, HDPE containers, nitrogen-flushed drums

  • Specification adjustments for moisture, assay, or impurity thresholds

  • Custom labeling and export documentation

Yes. According to GHS/UN regulations, 3,5-Dimethylpiperidine is flammable and requires:

  • UN-compliant packaging

  • Shipping as Class 3 flammable liquid

  • Proper labeling and documentation in line with ADR/IMDG/IATA codes

Our supply chain complies with:

  • ISO 9001:2015 Quality Management System

  • Batch-level COA, MSDS, TDS

  • Export documentation including Certificate of Origin, Reach pre-registration (if applicable)

  • Store in tightly sealed containers under nitrogen or argon

  • Recommended storage temperature: 5°C to 30°C

  • Avoid exposure to moisture, oxygen, or direct sunlight

  • Sample orders: 2–4 working days

  • Bulk orders: 7–12 working days depending on volume

  • Shipping via FedEx, DHL, air freight, or sea freight with full documentation

Yes. Our team offers:

  • Analytical method guidance (GC, KF, NMR)

  • Assistance with regulatory submissions

  • 24h response to technical inquiries regarding handling, formulation, or process safety

  • Strict quality control with GC/HPLC/NMR verification

  • Batch-to-batch consistency for sensitive synthesis

  • Support for both lab-scale and commercial-scale supply

  • Trusted by API manufacturers and agrochemical innovators in 20+ countries

Can’t find your question here? Our team is ready to assist you 1-on-1.

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